Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 2/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 17/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25840608 | 0.87 | POLH (0.87) | POLHALOX5 | |
| SCHEMBL27556820 | 0.86 | KDM4E (0.60) | POLHALOX5 | |
| SCHEMBL25308157 | 0.80 | POLH (1.00) | POLHALOX5 | |
| SCHEMBL30663833 | 0.80 | POLH (1.00) | POLHALOX5 | |
| SCHEMBL18676308 | 0.78 | MEN1 (0.72) | POLHALOX5 | |
| SCHEMBL29826664 | 0.78 | MEN1 (0.72) | POLHALOX5 | |
| SCHEMBL31326068 | 0.78 | MEN1 (0.72) | POLHALOX5 | |
| SCHEMBL7202185 | 0.74 | POLH (0.82) | POLHALOX5 | |
| SCHEMBL15928803 | 0.74 | POLH (0.72) | POLHALOX5 | |
| SCHEMBL5169608 | 0.73 | POLH (0.80) | POLHALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215522-A1 | DERIVATIVES OF 4-CHROMONE AS INHIBITORS OF THE RDRP POLYMERASE OF SARS-COV-2 VIRUS AND METHOD FOR THE PREPARATION THEREOF | Fondazione Istituto Italiano di Tecnologia (IT) | 2023-07-26 | — | — | EP | disclosed |