Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.72 |
| ▸ | MAPT | P10636 | 8/20 | 0.72 |
| ▸ | TP53 | P04637 | 6/20 | 0.72 |
| ▸ | RECQL | P46063 | 6/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.72 |
| ▸ | APP | P05067 | 4/20 | 0.72 |
| ▸ | IP6K2 | Q9UHH9 | 4/20 | 0.72 |
| ▸ | SLCO2B1 | O94956 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18676308 | 1.00 | MEN1 (0.72) | MEN1KMT2AKDM4ECYP3A4HSD17B10 | |
| SCHEMBL31326068 | 1.00 | MEN1 (0.72) | MEN1KMT2AKDM4ECYP3A4HSD17B10 | |
| SCHEMBL12639983 | 0.88 | MEN1 (0.74) | MEN1KMT2AKDM4ECYP3A4HSD17B10 | |
| Quercetin SCHEMBL729498 | 0.86 | MEN1 (0.76) | MEN1KMT2AKDM4ECYP3A4HSD17B10 | |
| SCHEMBL22625755 | 0.85 | MEN1 (0.61) | MEN1KMT2AKDM4ECYP3A4HSD17B10 | |
| SCHEMBL10335363 | 0.84 | MEN1 (0.79) | MEN1KMT2AKDM4ECYP3A4HSD17B10 | |
| SCHEMBL4879748 | 0.84 | AMY1A (0.78) | MEN1KMT2AKDM4ECYP3A4HSD17B10 | |
| SCHEMBL7660030 | 0.84 | NOX4 (0.76) | MEN1KMT2AKDM4ECYP3A4HSD17B10 | |
| SCHEMBL14764339 | 0.84 | MEN1 (0.76) | MEN1KMT2AKDM4ECYP3A4HSD17B10 | |
| SCHEMBL14764381 | 0.84 | CYP1A1 (0.76) | MEN1KMT2AKDM4ECYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981263-A | Novel quercetin redox derivatives and use thereof as BET inhibitors | 贝诺生物有限公司 | 2022-08-30 | — | — | CN | disclosed |