Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 5/20 | 0.87 |
| ▸ | ALOX5 | P09917 | 13/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | BCL9 | O00512 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | MGAM | O43451 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30663833 | 0.93 | POLH (1.00) | POLHALOX5MEN1KMT2AKDM4E | |
| SCHEMBL25308157 | 0.93 | POLH (1.00) | POLHALOX5MEN1KMT2AKDM4E | |
| SCHEMBL7202185 | 0.88 | POLH (0.82) | POLHALOX5MEN1KMT2AKDM4E | |
| SCHEMBL25841205 | 0.87 | POLH (0.66) | POLHALOX5 | |
| SCHEMBL31485716 | 0.87 | POLH (0.80) | POLHALOX5MEN1KMT2AKDM4E | |
| SCHEMBL5169608 | 0.87 | POLH (0.80) | POLHALOX5MEN1KMT2AKDM4E | |
| SCHEMBL15928803 | 0.86 | POLH (0.72) | POLHALOX5MEN1KMT2AKDM4E | |
| Ophioglonol SCHEMBL30406715 | 0.84 | POLH (0.76) | POLHALOX5MEN1KMT2AKDM4E | |
| SCHEMBL25262255 | 0.82 | POLH (1.00) | POLHALOX5MEN1KMT2AKDM4E | |
| SCHEMBL824468 | 0.81 | POLH (1.00) | POLHALOX5MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215522-A1 | DERIVATIVES OF 4-CHROMONE AS INHIBITORS OF THE RDRP POLYMERASE OF SARS-COV-2 VIRUS AND METHOD FOR THE PREPARATION THEREOF | Fondazione Istituto Italiano di Tecnologia (IT) | 2023-07-26 | — | — | EP | disclosed |