Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276559 | 0.83 | MMP1 (0.56) | EPHX1SMN1; SMN2PKMMMP1MMP2 | |
| SCHEMBL50404 | 0.80 | — | — | |
| SCHEMBL13036241 | 0.80 | — | — | |
| SCHEMBL862258 | 0.80 | — | — | |
| SCHEMBL12169104 | 0.79 | EPHX1 (0.42) | LMNAEPHX1SMN1; SMN2PKMMMP1 | |
| SCHEMBL20034129 | 0.76 | ALDH1A1 (0.55) | LMNAEPHX1SMN1; SMN2PKMMMP1 | |
| SCHEMBL22146086 | 0.76 | — | — | |
| SCHEMBL22571801 | 0.76 | — | — | |
| SCHEMBL606969 | 0.76 | — | — | |
| SCHEMBL23994365 | 0.75 | LMNA (0.46) | LMNAEPHX1PKMMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212524-A1 | CD73 INHIBITOR AND APPLICATION THEREOF IN MEDICINE | Betta Pharmaceuticals Co., Ltd (CN) | 2023-07-19 | — | — | EP | disclosed |