SCHEMBL25842189

SCHEMBL25842189

CC(C)=CCc1ccc2c(CC(C)N)c[nH]c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.54
HTR2C P28335 4/20 0.54
HTR1A P08908 3/20 0.54
HTR2B P41595 3/20 0.54
HTR1D P28221 2/20 0.54
HTR1B P28222 2/20 0.54
ADRB1 P08588 1/20 0.54
ADRA2A P08913 1/20 0.54
SLC6A2 P23975 1/20 0.54
HTR1E P28566 1/20 0.54
SLC6A4 P31645 1/20 0.54
HTR7 P34969 1/20 0.54
HTR6 P50406 1/20 0.54
SLC6A3 Q01959 1/20 0.54
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
NFKB1 P19838 1/20 0.52
CYP2C19 P33261 1/20 0.52
NPSR1 Q6W5P4 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25937517 0.88 PTPRA (0.46) HTR2AHTR2CHTR1AHTR2BHTR1D
SCHEMBL25304139 0.87 PTPRA (0.57) HTR2AHTR2CHTR1AHTR2BHTR1D
SCHEMBL25307935 0.87 PTPRA (0.57) HTR2AHTR2CHTR1AHTR2BHTR1D
SCHEMBL25842172 0.85 KDM4E (0.57) HTR2AHTR2CHTR1AHTR2BSLC6A4
SCHEMBL29804890 0.83 HTR2A (0.57) HTR2AHTR2CHTR1AHTR2BHTR1D
SCHEMBL25260689 0.83 HTR2A (0.57) HTR2AHTR2CHTR1AHTR2BHTR1D
SCHEMBL26202498 0.82 HTR2A (0.44) HTR2AHTR2CHTR1AHTR2BHTR1D
SCHEMBL25842178 0.81 HTR2A (0.42) HTR2AHTR2CHTR1AHTR2BHTR1D
SCHEMBL16433255 0.81 NPC1 (0.50) HTR2AHTR2CHTR1AHTR2BHTR1D
SCHEMBL31549198 0.79 ALDH1A1 (0.48) SLC6A2CYP2C9NFKB1NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219888-A1 PRENYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219888-A1 PRENYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING AANAT, ACAT2, PCYT1A HTR2A 1566/4885HTR2C 1158/4885HTR1A 1419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.