SCHEMBL25843161

SCHEMBL25843161

NOC1=NC(=O)C(C2C[C@@H](O)C(COP(=O)(O)OP(=O)(O)O)O2)C=C1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.38
P2RY6 Q15077 5/20 0.36
P2RY2 P41231 7/20 0.35
P2RY4 P51582 6/20 0.35
DUT P33316 1/20 0.35
POLA1 P09884 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20999060 0.77 P2RY2 (0.40) POLBP2RY6P2RY2P2RY4POLA1
SCHEMBL20999063 0.77 P2RY2 (0.39) POLBP2RY6P2RY2P2RY4POLA1
SCHEMBL20999061 0.76 P2RY2 (0.39) POLBP2RY6P2RY2P2RY4POLA1
SCHEMBL25843145 0.74 FBP1 (0.46) P2RY6P2RY2
SCHEMBL14665773 0.72 NT5E (0.36) P2RY6P2RY2P2RY4POLA1
SCHEMBL22986143 0.69 P2RY2 (0.40) P2RY6P2RY2P2RY4
SCHEMBL15689120 0.69 P2RY2 (0.44) POLBP2RY6P2RY2P2RY4DUT
SCHEMBL21016761 0.68 FBP1 (0.38) POLBP2RY6P2RY2P2RY4DUT
SCHEMBL16382553 0.68 P2RY2 (0.40) POLBP2RY6P2RY2P2RY4DUT
SCHEMBL19072605 0.67 P2RY2 (0.40) P2RY2P2RY4POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219994-A1 MODIFIED NUCLEOSIDE AND SYNTHESIS METHOD THEREFOR Stemirna Therapeutics Co., Ltd. (CN) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219994-A1 MODIFIED NUCLEOSIDE AND SYNTHESIS METHOD THEREFOR RNMT, RNGTT, BCDIN3D POLB 179/4885P2RY6 2965/4885P2RY2 3959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.