Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 18/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979718 | 0.81 | MAOB (1.00) | MAOBMEN1MIFACHEKMT2A | |
| SCHEMBL31179771 | 0.81 | MAOB (1.00) | MAOBMEN1MIFACHEKMT2A | |
| SCHEMBL29595747 | 0.81 | MAOB (1.00) | MAOBMEN1MIFACHEKMT2A | |
| SCHEMBL979717 | 0.81 | MAOB (1.00) | MAOBMEN1MIFACHEKMT2A | |
| SCHEMBL8085340 | 0.78 | MAOB (0.62) | MAOBMEN1MIFACHEKMT2A | |
| SCHEMBL29152102 | 0.77 | MIF (0.66) | MAOBMEN1MIFACHEKMT2A | |
| SCHEMBL13417545 | 0.74 | MAOB (0.66) | MAOBMEN1MIFACHEKMT2A | |
| SCHEMBL5859220 | 0.74 | MAOB (0.65) | MAOBMEN1MIFACHEKMT2A | |
| SCHEMBL21082590 | 0.74 | STK17B (0.66) | MAOBMEN1ACHEKMT2ATDP1 | |
| SCHEMBL5859226 | 0.74 | MAOB (0.65) | MAOBMEN1MIFACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215522-A1 | DERIVATIVES OF 4-CHROMONE AS INHIBITORS OF THE RDRP POLYMERASE OF SARS-COV-2 VIRUS AND METHOD FOR THE PREPARATION THEREOF | Fondazione Istituto Italiano di Tecnologia (IT) | 2023-07-26 | — | — | EP | disclosed |