Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.61 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.61 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.60 |
| ▸ | ELANE | P08246 | 4/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355364 | 0.83 | PIK3C3 (0.65) | STK17BMEN1KMT2AMAPK1USP2 | |
| (Z)-Aurone SCHEMBL31266594 | 0.80 | STK17B (1.00) | STK17BMEN1KMT2AMAPK1ELANE | |
| (Z)-Aurone SCHEMBL29935711 | 0.80 | STK17B (1.00) | STK17BMEN1KMT2AMAPK1ELANE | |
| (Z)-Aurone SCHEMBL305101 | 0.80 | STK17B (1.00) | STK17BMEN1KMT2AMAPK1ELANE | |
| (Z)-Aurone SCHEMBL13971324 | 0.80 | STK17B (1.00) | STK17BMEN1KMT2AMAPK1ELANE | |
| (Z)-Aurone SCHEMBL305100 | 0.80 | STK17B (1.00) | STK17BMEN1KMT2AMAPK1ELANE | |
| SCHEMBL22827822 | 0.76 | STK17B (0.59) | STK17BMEN1KMT2AMAPK1ELANE | |
| SCHEMBL19462733 | 0.74 | STK17B (0.89) | STK17BMEN1KMT2AMAPK1MAPT | |
| SCHEMBL19499394 | 0.74 | STK17B (0.89) | STK17BMEN1KMT2AMAPK1MAPT | |
| SCHEMBL25843205 | 0.74 | MAOB (0.68) | MEN1KMT2AMAPTLMNAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053933-A1 | THERAPEUTIC AURONES | Middle Tennessee State University (US) | 2021-02-25 | — | — | US | disclosed |
| US-20200399238-A1 | THERAPEUTIC AURONES | Middle Tennessee State University (US) | 2020-12-24 | — | — | US | disclosed |
| WO-2020223439-A1 | AURONES AND METHODS OF USING AURONES TO TREAT TUBERCULOSIS | Middle Tennessee State University (US) | 2020-11-05 | — | — | WO | disclosed |
| US-20190169151-A1 | THERAPEUTIC AURONES | Middle Tennessee State University (US) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399238-A1 | THERAPEUTIC AURONES | AURKA, PIGS, PRF1 | STK17B 1615/4885MEN1 2702/4885KMT2A 2551/4885 |
| US-20210053933-A1 | THERAPEUTIC AURONES | AURKA, PIGS, PRF1 | STK17B 1615/4885MEN1 2702/4885KMT2A 2551/4885 |
| US-20190169151-A1 | THERAPEUTIC AURONES | AURKA, PIGS, PRF1 | STK17B 1615/4885MEN1 2702/4885KMT2A 2551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.