Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25844011 | 0.98 | TP53 (0.32) | TP53MAPTGPR84KDM4EMEN1 | |
| SCHEMBL25844151 | 0.97 | MAPT (0.31) | TP53MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL25844182 | 0.96 | GPR84 (0.34) | TP53MAPTGPR84KDM4EMEN1 | |
| SCHEMBL25844185 | 0.96 | GPR84 (0.34) | TP53MAPTGPR84KDM4EMEN1 | |
| SCHEMBL25844013 | 0.95 | LTA4H (0.32) | TP53MAPTGPR84KDM4EALDH1A1 | |
| SCHEMBL25844693 | 0.95 | TP53 (0.33) | TP53MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL25844048 | 0.94 | — | — | |
| SCHEMBL25529761 | 0.93 | TP53 (0.32) | TP53MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL25844692 | 0.93 | KDM4E (0.34) | TP53MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL25844007 | 0.92 | LMNA (0.30) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227717-A1 | PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-07-20 | — | — | US | disclosed |