Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25844259 | 0.82 | TRPA1 (0.48) | RBP4TRPA1TRPV1 | |
| SCHEMBL23064385 | 0.82 | TRPA1 (0.51) | TRPA1TRPV1KDM4EHSD17B10KCNH2 | |
| SCHEMBL23064386 | 0.82 | TRPA1 (0.51) | TRPA1TRPV1KDM4EHSD17B10KCNH2 | |
| SCHEMBL26814990 | 0.82 | P2RY12 (0.44) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL23283045 | 0.82 | P2RY12 (0.47) | — | |
| SCHEMBL24835211 | 0.74 | P2RY12 (0.47) | HPGD | |
| SCHEMBL30633886 | 0.70 | TRPA1 (0.52) | RBP4TRPA1TRPV1MALT1HSD17B10 | |
| SCHEMBL23064252 | 0.70 | TRPA1 (0.52) | RBP4TRPA1TRPV1MALT1HSD17B10 | |
| SCHEMBL4321939 | 0.68 | RBP4 (0.51) | RBP4MALT1KDM4EALDH1A1 | |
| SCHEMBL23733258 | 0.68 | P2RY12 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023163203-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING RENAL DISEASE | 国立大学法人大阪大学 | 2023-08-31 | — | — | WO | disclosed |
| WO-2023132208-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING HEART FAILURE | 国立大学法人大阪大学 | 2023-07-13 | — | — | WO | disclosed |