Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.81 |
| ▸ | RAB9A | P51151 | 2/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1208088 | 0.82 | SMN1; SMN2 (0.84) | SMN1; SMN2RAB9AL3MBTL1GAAPOLB | |
| SCHEMBL12584934 | 0.82 | SMN1; SMN2 (0.84) | SMN1; SMN2RAB9AL3MBTL1GAAPOLB | |
| SCHEMBL5256770 | 0.81 | RAB9A (0.53) | SMN1; SMN2RAB9AL3MBTL1GAAPOLB | |
| SCHEMBL8790936 | 0.81 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9AL3MBTL1GAAPOLB | |
| SCHEMBL13932030 | 0.81 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9AL3MBTL1GAAPOLB | |
| SCHEMBL8791216 | 0.81 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9AL3MBTL1GAAPOLB | |
| SCHEMBL14003534 | 0.80 | L3MBTL1 (1.00) | SMN1; SMN2RAB9AL3MBTL1GAAPOLB | |
| SCHEMBL8791412 | 0.78 | RAB9A (0.75) | SMN1; SMN2RAB9AL3MBTL1GAAPOLB | |
| SCHEMBL8299157 | 0.78 | GAA (1.00) | SMN1; SMN2RAB9AL3MBTL1GAAPOLB | |
| SCHEMBL1208101 | 0.77 | SMN1; SMN2 (0.72) | SMN1; SMN2RAB9AL3MBTL1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122212-A2 | SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS | SOUTHERN RESEARCH INSTITUTE (US) | 2023-06-29 | — | — | WO | disclosed |