SCHEMBL258456

SCHEMBL258456

CCCCCOP(O)OCCCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA9 Q16790 3/20 0.41
THRB P10828 2/20 0.41
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
LPAR3 Q9UBY5 6/20 0.39
LPAR2 Q9HBW0 5/20 0.39
LPAR1 Q92633 2/20 0.39
NAAA Q02083 1/20 0.39
RECQL P46063 2/20 0.38
TSHR P16473 2/20 0.38
CES2 O00748 1/20 0.38
GLA P06280 1/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.38
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL164843 0.97 THRB (0.44) CA12CA1CA2CA9THRB
SCHEMBL1260510 0.97 THRB (0.44) CA12CA1CA2CA9THRB
SCHEMBL6267890 0.97 THRB (0.44) CA12CA1CA2CA9THRB
SCHEMBL6272715 0.97 THRB (0.44) CA12CA1CA2CA9THRB
SCHEMBL164198 0.97 THRB (0.44) CA12CA1CA2CA9THRB
SCHEMBL258773 0.97 THRB (0.44) CA12CA1CA2CA9THRB
SCHEMBL14351508 0.97 THRB (0.44) CA12CA1CA2CA9THRB
SCHEMBL258261 0.97 THRB (0.44) CA12CA1CA2CA9THRB
SCHEMBL15722834 0.97 THRB (0.44) CA12CA1CA2CA9THRB
SCHEMBL456550 0.97 THRB (0.44) CA12CA1CA2CA9THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 635 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114736238-B Protein carboxyl phosphorylation labeling reagent containing stable isotope, and preparation method and application thereof 广东磷基生物科技有限公司 2024-05-24 CN claimed
US-20240043766-A1 SYNTHETIC ESTER AND MINERAL OIL DIELECTRIC FLUIDS WITH INCREASED STABILITY CARGILL, INCORPORATED (US) 2024-02-08 US claimed
CN-117264188-A Preparation method and application of polyester with degradation stability 四川大学 2023-12-22 CN claimed
US-11814598-B2 Synthetic ester and mineral oil dielectric fluids with increased stability CARGILL, INCORPORATED (US) 2023-11-14 US claimed
CN-114736238-A Protein carboxyl phosphorylation labeling reagent containing stable isotope and preparation method and application thereof 厦门大学 2022-07-12 CN claimed
EP-2481760-B1 INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP claimed
EP-3797430-A1 DIELECTRIC FLUIDS COMPRISING NATURAL BIO-SOURCED OIL WITH INCREASED STABILITY Cargill, Incorporated (US) 2021-03-31 EP claimed
US-20210027910-A1 SYNTHETIC ESTER AND MINERAL OIL DIELECTRIC FLUIDS WITH INCREASED STABILITY CARGILL, INCORPORATED (US) 2021-01-28 US claimed
US-20210027911-A1 DIELECTRIC FLUIDS COMPRISING NATURAL BIO-SOURCED OIL WITH INCREASED STABILITY CARGILL, INCORPORATED (US) 2021-01-28 US claimed
EP-3769322-A1 SYNTHETIC ESTER AND MINERAL OIL DIELECTRIC FLUIDS WITH INCREASED STABILITY Cargill, Incorporated (US) 2021-01-27 EP claimed
US-7723276-B2 Oil for cutting and grinding by ultra low volume oil feed system and for sliding surface and method for cutting and grinding by ultra low volume feed system using the oil NIPPON OIL CORPORATION (JP) 2010-05-25 US claimed
US-20090221787-A1 Production Of Monomer, Oligomer And Polymer Phosphonic Acid Esters And Phosphonic And Sulphonic Acids By A Nucleophile Aromatic Substitution HARING THOMAS 2009-09-03 US claimed
EP-1360222-B1 ORGANOPOLYSILOXANES CONTAINING PHOSPHONIC GROUPS, METHODS FOR THE PRODUCTION AND USE THEREOF PHOSPHONICS LTD (GB) 2006-09-06 EP claimed
EP-1011839-B1 METHOD FOR ADSORBING ORGANOPHOSPHORUS COMPOUNDS CONTAINED IN A LIQUID RHODIA CHIMIE SA (FR) 2005-04-06 EP claimed
US-6316575-B1 MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed
US-4692426-A Phosphite-promoted ruthenium-cobalt catalysts for the dealkoxyhydroxymethylation of acetals to form glycol ethers SUN REFINING AND MARKETING COMPANY (US) 1987-09-08 US claimed
EP-0155165-A2 Process for introducing phosphinoyl groups into amino groups AJINOMOTO CO., INC. (JP) 1985-09-18 EP claimed
US-4132724-A Preparation of organoaluminum compositions MANCHEM LIMITED (GB) 1979-01-02 US claimed
US-4064200-A FROM A DIESTER OF PHOSPHOROUS ACID, SULFUR AND A BENZYL HALIDE, EXTRACTION IHARA CHEMICAL KOGYO KABUSHIKI KAISHA (JA) 1977-12-20 US claimed
US-4022852-A SULFAMIDE, FORMALDEHYDE, DIALKYL-DIARYL-PHOSPHITE HOECHST AKTIENGESELLSCHAFT (DT) 1977-05-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221787-A1 Production Of Monomer, Oligomer And Polymer Phosphonic Acid Esters And Phosphonic And Sulphonic Acids By A Nucleophile Aromatic Substitution PFKFB2, PFKFB4, PFKFB1 CA12 1248/4885CA1 1698/4885CA2 546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.