Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK2 | P53671 | 1/20 | 0.56 |
| ▸ | MC4R | P32245 | 5/20 | 0.53 |
| ▸ | MC3R | P41968 | 5/20 | 0.53 |
| ▸ | MC5R | P33032 | 4/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3795459 | 0.93 | MC4R (0.61) | LIMK2MC4RMC3RMC5RREN | |
| SCHEMBL27075772 | 0.93 | MC4R (0.61) | LIMK2MC4RMC3RMC5RREN | |
| SCHEMBL1023411 | 0.89 | CARM1 (0.55) | LIMK2MC4RMC3RRENTDP1 | |
| SCHEMBL3383363 | 0.87 | MAOA (0.57) | MC4RMC3RMC5RADRA2C | |
| Hydrochloric Acid SCHEMBL570912 | 0.87 | CARM1 (0.53) | LIMK2MC4RMC3RRENTDP1 | |
| SCHEMBL21628078 | 0.86 | REN (0.56) | MC4RMC3RMC5RRENTDP1 | |
| SCHEMBL3382221 | 0.86 | MAOA (0.55) | MC4RMC3RMC5RTDP1MEN1 | |
| SCHEMBL2076709 | 0.85 | CCR6 (0.59) | LIMK2MC4RMC3RMC5RTDP1 | |
| SCHEMBL8331046 | 0.84 | CA12 (0.50) | LIMK2MC4RMC3RMC5RTDP1 | |
| SCHEMBL4207867 | 0.83 | HDAC1 (0.57) | RENTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563847-B1 | MCR DENDRIMERS | LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) | 2016-04-13 | — | — | EP | disclosed |
| EP-2563847-A1 | MCR DENDRIMERS | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011134607-A1 | MCR DENDRIMERS | LEIBNIZ-INSTITUT FÜR PFLANZENBIOCHEMIE (DE) | 2011-11-03 | — | — | WO | disclosed |
| US-7214715-B2 | Compounds to treat Alzheimer's disease | PHARMACIA & UPJOHN (US) | 2007-05-08 | — | — | US | disclosed |