Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23783083 | 0.87 | CRBN (0.61) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL23783020 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LMNAKCNJ1KCNH2KDM4E | |
| SCHEMBL30304379 | 0.84 | FAAH (0.54) | CRBNDDB1 | |
| SCHEMBL27091692 | 0.80 | DDB1 (0.58) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL23783169 | 0.80 | DDB1 (0.52) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL30919585 | 0.80 | DDB1 (0.52) | CRBNDDB1HDAC3HDAC1HDAC2 | |
| SCHEMBL8656203 | 0.80 | CRBN (0.65) | LMNACRBNDDB1POLB | |
| SCHEMBL25845862 | 0.79 | RXFP1 (0.51) | ALDH1A1LMNACRBNDDB1KDM4E | |
| SCHEMBL29554955 | 0.79 | RXFP1 (0.51) | ALDH1A1LMNACRBNDDB1KDM4E | |
| SCHEMBL31323602 | 0.79 | DDB1 (0.52) | CRBNDDB1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691972-B2 | Compounds for targeted degradation of BRD9 | C4 THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691972-B2 | Compounds for targeted degradation of BRD9 | BRD9, BRD1, BRWD1 | ALDH1A1 4230/4885LMNA 2718/4885KCNJ1 3635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.