SCHEMBL8656203

SCHEMBL8656203

O=C1CCC(Nc2ccc([N+](=O)[O-])cc2)C(=O)N1

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 0.65
DDB1 Q16531 18/20 0.65
LMNA P02545 1/20 0.51
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30817325 0.90 CRBN (0.69) CRBNDDB1POLB
SCHEMBL30304379 0.81 FAAH (0.54) CRBNDDB1
SCHEMBL25845854 0.80 ALDH1A1 (0.50) CRBNDDB1LMNAPOLB
SCHEMBL4390832 0.80 CRBN (0.53) CRBNDDB1LMNAMAPT
SCHEMBL19359545 0.80 MEN1 (0.57) CRBNDDB1POLB
SCHEMBL23551584 0.79 DDB1 (0.72) CRBNDDB1
SCHEMBL21965374 0.79 DDB1 (0.72) CRBNDDB1
SCHEMBL21965393 0.79 DDB1 (1.00) CRBNDDB1
SCHEMBL31554764 0.79 CRBN (1.00) CRBNDDB1
SCHEMBL23551219 0.79 DDB1 (0.72) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5719690-A Photorefractive glass article INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-02-17 US disclosed