Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418893 | 0.89 | ALDH1A1 (0.75) | BCAT2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6236939 | 0.88 | ALDH1A1 (0.68) | BCAT2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL25676620 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27412441 | 0.80 | CRBN (0.68) | BCAT2ALDH1A1HPGDCHRNA7CHRNA10 | |
| SCHEMBL2639481 | 0.78 | F10 (0.52) | BCAT2ALDH1A1HPGD | |
| SCHEMBL3371018 | 0.78 | BCAT2 (0.46) | BCAT2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL25846387 | 0.78 | DDB1 (0.60) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25240846 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4240116 | 0.76 | KMT2A (0.53) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1377551 | 0.74 | CHRNA7 (0.54) | BCAT2ALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122212-A2 | SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS | SOUTHERN RESEARCH INSTITUTE (US) | 2023-06-29 | — | — | WO | disclosed |