SCHEMBL3371018

SCHEMBL3371018

NC(=O)c1ccc(N2CCNCC2=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.46
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
ALDH1A1 P00352 5/20 0.44
MAPKAPK2 P49137 1/20 0.44
OPRD1 P41143 1/20 0.43
ACVR1 Q04771 1/20 0.43
HSP90AA1 P07900 1/20 0.42
HSP90AB1 P08238 1/20 0.42
OPRM1 P35372 1/20 0.40
OPRL1 P41146 1/20 0.40
HPGD P15428 3/20 0.39
USP2 O75604 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CHRNA7 P36544 1/20 0.38
CHRNA10 Q9GZZ6 1/20 0.38
CHRNA9 Q9UGM1 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3770189 0.84 L3MBTL1 (0.49) SLC6A2SLC6A4SLC6A3ALDH1A1MAPKAPK2
SCHEMBL85663 0.82 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3ALDH1A1MAPKAPK2
SCHEMBL1584076 0.80 SLC6A2 (0.49) SLC6A2SLC6A4SLC6A3ALDH1A1MAPKAPK2
Hydrochloric Acid SCHEMBL1583739 0.79 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3ALDH1A1MAPKAPK2
SCHEMBL25845878 0.78 BCAT2 (0.59) BCAT2ALDH1A1HPGDTSHRCHRNA7
SCHEMBL4396319 0.78 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3ALDH1A1MAPKAPK2
SCHEMBL3656969 0.78 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3ALDH1A1MAPKAPK2
SCHEMBL25240100 0.77 ALDH1A1 (0.51) ALDH1A1HSP90AA1HPGDTSHRHSD17B10
SCHEMBL30949227 0.77 SLC6A2 (0.38) SLC6A2SLC6A4SLC6A3ALDH1A1OPRD1
Hydrochloric Acid SCHEMBL1583516 0.77 SLC6A2 (0.51) SLC6A2SLC6A4SLC6A3ALDH1A1MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110819291-B Polyurethane adhesive for battery flexible package 中国乐凯集团有限公司 2022-04-15 CN claimed
CN-110819291-A Polyurethane adhesive for battery flexible package 中国乐凯集团有限公司 2020-02-21 CN claimed
CN-109421221-A A kind of drainpipe injection mold for building 李才英 2019-03-05 CN claimed
CN-108864974-A ANTISTATIC SURFACE PROTECTIVE FILM 藤森工业株式会社 2018-11-23 CN claimed
CN-107537565-A Cross linked amphoteric polymeric supported precious metal catalyst and preparation and alcohol method for oxidation 中国科学院大连化学物理研究所 2018-01-05 CN claimed
CN-206374120-U A kind of drainpipe injection mold for building 浙江吉天建设有限公司 2017-08-04 CN claimed
EP-1636216-B1 BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS SANOFI AVENTIS DEUTSCHLAND (DE) 2010-07-21 EP claimed
US-7741341-B2 Benzimidazole-derivatives as factor Xa inhibitors SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2010-06-22 US claimed
JP-2006528213-A 2006-12-14 JP claimed
EP-1636216-A1 BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS Sanofi-Aventis Deutschland GmbH (DE) 2006-03-22 EP claimed
US-20050009829-A1 Benzimidazole-derivatives as factor Xa inhibitors AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2005-01-13 US claimed
WO-2004101553-A1 BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2004-11-25 WO claimed
CN-1017440-B Flame-retardant resin composition IDEMITSU KOSAN CO (JP) 1992-07-15 CN claimed
CN-117683500-A Lithium battery aluminum plastic film outer layer interlayer adhesive and preparation method thereof 沈阳化工研究院有限公司 2024-03-12 CN disclosed
US-20230265054-A1 PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING GENENTECH, INC. (US) 2023-08-24 US disclosed
CN-115850269-A Tetrahydro-beta-carboline compound and preparation method and application thereof 南京工业大学 2023-03-28 CN disclosed
EP-0527574-A1 Image forming apparatus KONICA CORPORATION (JP) 1993-02-17 EP disclosed
US-4612356-A Homo- and co- (addition) polymers of di-perfluoroalkyl carbamyl group containing (meth) acrylate monomers CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed
US-4584143-A USED IN FINISHES AND POLYMERS CIBA GEIGY CORPORATION (US) 1986-04-22 US disclosed
US-4540805-A HYDROPHOBIC AND OLEOPHOBIC FINISHES CIBA-GEIGY CORPORATION (US) 1985-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265054-A1 PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING SHH, GLI1, SMO BCAT2 3816/4885SLC6A2 4842/4885SLC6A4 4548/4885
US-20050009829-A1 Benzimidazole-derivatives as factor Xa inhibitors F12, F11, F5 BCAT2 397/4885SLC6A2 4650/4885SLC6A4 4617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.