SCHEMBL25846016

SCHEMBL25846016

O=C(O)CC1COc2cc(OCc3cc(Cl)cc4c3OCCO4)ccc21

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 18/20 0.60
PPARD Q03181 11/20 0.60
PPARG P37231 10/20 0.60
PPARA Q07869 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25844251 0.93 FFAR1 (0.61) FFAR1PPARDPPARGPPARA
SCHEMBL25845928 0.93 FFAR1 (0.61) FFAR1PPARDPPARGPPARA
SCHEMBL25845361 0.90 FFAR1 (0.49) FFAR1PPARDPPARG
SCHEMBL25846029 0.88 PPARD (0.57) FFAR1PPARDPPARGPPARA
SCHEMBL25846001 0.88 FFAR1 (0.60) FFAR1PPARDPPARGPPARA
SCHEMBL25846148 0.87 PPARG (0.63) FFAR1PPARDPPARGPPARA
SCHEMBL25846464 0.85 FFAR1 (0.56) FFAR1PPARDPPARGPPARA
SCHEMBL25846205 0.85 FFAR1 (0.56) FFAR1PPARDPPARGPPARA
SCHEMBL25845317 0.83 FFAR1 (0.49) FFAR1PPARDPPARG
SCHEMBL25845503 0.83 FFAR1 (0.49) FFAR1PPARDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230339919-A1 BENZO OXYGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICAL APPLICATION THEREOF AB Pharma Ltd. (CN) 2023-10-26 US disclosed
US-20230339919-A1 BENZO OXYGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICAL APPLICATION THEREOF AB Pharma Ltd. (CN) 2023-10-26 US disclosed
EP-4212528-A1 BENZO OXYGEN-CONTAINING HETEROCYCLIC COMPOUND AND MEDICAL APPLICATION THEREOF AB Pharma Ltd. (CN) 2023-07-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339919-A1 BENZO OXYGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICAL APPLICATION THEREOF GPR55, GPR65, GPR4 FFAR1 52/4885PPARD 141/4885PPARG 73/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.