SCHEMBL25846320

SCHEMBL25846320

O=C(CCOCCNC(=O)OCC1c2ccccc2-c2ccccc21)OC(c1ccccc1)(c1ccc(C2CCCCCCCCC2)cc1)c1ccccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.41
▸ FABP7 O15540 1/20 0.34
▸ FABP5 Q01469 1/20 0.34
▸ TLR2 O60603 4/20 0.33
▸ TLR1 Q15399 2/20 0.33
▸ OPRD1 P41143 1/20 0.32
▸ P2RY14 Q15391 1/20 0.32
▸ FFAR2 O15552 1/20 0.31
▸ KIF11 P52732 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ EPHX2 P34913 1/20 0.31
▸ OPRL1 P41146 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25846454 0.97 KMT2A (0.39) KMT2AFABP7FABP5TLR2TLR1
SCHEMBL26045350 0.97 KMT2A (0.39) KMT2AFABP7FABP5TLR2TLR1
SCHEMBL25658804 0.93 KMT2A (0.44) KMT2AFABP7FABP5TLR2TLR1
SCHEMBL25658818 0.93 KMT2A (0.44) KMT2AFABP7FABP5TLR2TLR1
SCHEMBL25658800 0.93 KMT2A (0.44) KMT2AFABP7FABP5TLR2TLR1
SCHEMBL23156981 0.93 KMT2A (0.44) KMT2AFABP7FABP5TLR2TLR1
SCHEMBL24579138 0.89 KMT2A (0.39) KMT2AFABP7FABP5TLR2TLR1
SCHEMBL18177182 0.88 KMT2A (0.44) KMT2AFABP7FABP5TLR2LMNA
SCHEMBL17751582 0.87 KMT2A (0.44) KMT2AFABP7FABP5TLR2LMNA
SCHEMBL25835592 0.87 KMT2A (0.44) KMT2AFABP7FABP5TLR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 KMT2A 1603/4885FABP7 100/4885FABP5 304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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