SCHEMBL26045350

SCHEMBL26045350

O=C(CCOCCNC(=O)OCC1c2ccccc2-c2ccccc21)NCCOCCC(=O)OC(c1ccccc1)(c1ccc(C2CCCCCCCC2)cc1)c1ccccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.39
▸ TLR2 O60603 3/20 0.33
▸ FABP7 O15540 1/20 0.32
▸ FABP5 Q01469 1/20 0.32
▸ TLR1 Q15399 1/20 0.32
▸ SLC9A3 P48764 4/20 0.31
▸ P2RY14 Q15391 1/20 0.30
▸ OPRD1 P41143 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ FFAR2 O15552 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25846454 1.00 KMT2A (0.39) KMT2ATLR2FABP7FABP5TLR1
SCHEMBL25846320 0.97 KMT2A (0.41) KMT2ATLR2FABP7FABP5TLR1
SCHEMBL25658818 0.91 KMT2A (0.44) KMT2ATLR2FABP7FABP5TLR1
SCHEMBL25658800 0.91 KMT2A (0.44) KMT2ATLR2FABP7FABP5TLR1
SCHEMBL25658804 0.91 KMT2A (0.44) KMT2ATLR2FABP7FABP5TLR1
SCHEMBL23156981 0.91 KMT2A (0.44) KMT2ATLR2FABP7FABP5TLR1
SCHEMBL24579138 0.87 KMT2A (0.39) KMT2ATLR2FABP7FABP5TLR1
SCHEMBL18177182 0.85 KMT2A (0.44) KMT2ATLR2FABP7FABP5
SCHEMBL17751582 0.85 KMT2A (0.44) KMT2ATLR2FABP7FABP5
SCHEMBL25835592 0.85 KMT2A (0.44) KMT2ATLR2FABP7FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 KMT2A 3122/4885TLR2 3599/4885FABP7 598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback