Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10671008 | 0.96 | PDE10A (0.47) | HPGDSPDE10ACYP1A2KDM4EALDH1A1 | |
| SCHEMBL16189336 | 0.93 | KMT2A (0.50) | HPGDSPDE10ACYP1A2DHODHKDM4E | |
| SCHEMBL17932793 | 0.93 | KMT2A (0.50) | HPGDSPDE10ACYP1A2DHODHKDM4E | |
| SCHEMBL16189425 | 0.91 | KMT2A (0.51) | HPGDSPDE10ACYP1A2KDM4EALDH1A1 | |
| SCHEMBL25847343 | 0.89 | CYP1A2 (0.42) | HPGDSPDE10ACYP1A2KDM4EALDH1A1 | |
| SCHEMBL29118695 | 0.89 | ALDH1A1 (0.51) | HPGDSCYP1A2KDM4EALDH1A1ADORA2A | |
| SCHEMBL16189098 | 0.88 | MEN1 (0.46) | HPGDSCYP1A2DHODHALDH1A1MAPT | |
| SCHEMBL17932795 | 0.88 | MEN1 (0.46) | HPGDSCYP1A2DHODHALDH1A1MAPT | |
| SCHEMBL8473236 | 0.86 | HPGDS (0.43) | HPGDSCYP1A2KDM4EALDH1A1ADORA2A | |
| SCHEMBL10989756 | 0.86 | CRHR1 (0.47) | HPGDSCYP1A2KDM4EALDH1A1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186003-A | Preparation method of isoquinoline derivative | 苏州大学 | 2023-12-08 | — | — | CN | disclosed |
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | KCNQ2, KCNQ1, KCNQ4 | HPGDS 3441/4885PDE10A 4030/4885CYP1A2 1154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.