Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12350657 | 1.00 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4CASP1 | |
| SCHEMBL28179585 | 0.86 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4CASP1 | |
| SCHEMBL19485537 | 0.85 | CNR1 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4CASP1 | |
| SCHEMBL22417752 | 0.82 | CASP1 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4CASP1 | |
| SCHEMBL4808526 | 0.80 | — | — | |
| SCHEMBL4808522 | 0.80 | — | — | |
| SCHEMBL20008159 | 0.77 | — | — | |
| SCHEMBL18290117 | 0.77 | CASP1 (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4CASP1 | |
| SCHEMBL9541336 | 0.74 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4OXER1 | |
| SCHEMBL12619157 | 0.74 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4OXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212552-A1 | ANTI-HER2 ANTIBODY-DRUG CONJUGATE | Daiichi Sankyo Company, Limited (JP) | 2023-07-19 | — | — | EP | disclosed |