Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18522222 | 1.00 | LMNA (0.42) | LMNAITGB1ITGA5FAAHALDH1A1 | |
| SCHEMBL18088416 | 0.98 | LMNA (0.43) | LMNAITGB1ITGA5FAAHALDH1A1 | |
| SCHEMBL19674373 | 0.86 | LMNA (0.37) | LMNAITGB1ITGA5FAAHALDH1A1 | |
| SCHEMBL29756951 | 0.84 | ECE1 (0.47) | LMNAFAAHMEN1KMT2AMAPT | |
| SCHEMBL4968451 | 0.80 | FAAH (0.37) | LMNAITGB1ITGA5FAAHALDH1A1 | |
| SCHEMBL19672582 | 0.80 | ALDH1A1 (0.39) | LMNAITGB1ITGA5FAAHALDH1A1 | |
| SCHEMBL24287064 | 0.80 | LMNA (0.41) | LMNAFAAHALDH1A1KMT2A | |
| SCHEMBL25100357 | 0.80 | LMNA (0.41) | LMNAFAAHALDH1A1KMT2A | |
| SCHEMBL24285705 | 0.80 | LMNA (0.41) | LMNA | |
| SCHEMBL25962591 | 0.80 | LMNA (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137026-A1 | CAMPTOTHECIN ANALOGS CONJUGATED TO A GLUTAMINE RESIDUE IN A PROTEIN, AND THEIR USE | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-20 | — | — | WO | disclosed |