Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.36 |
| ▸ | NOS2 | P35228 | 4/20 | 0.36 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729409 | 0.80 | KDM4E (0.38) | HSP90AA1HSP90AB1AXLPRKCIKDM4E | |
| SCHEMBL30082527 | 0.80 | KDM4E (0.38) | HSP90AA1HSP90AB1AXLPRKCIKDM4E | |
| SCHEMBL30515887 | 0.80 | MEN1 (0.37) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL21579429 | 0.80 | MEN1 (0.37) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL25259410 | 0.77 | MEN1 (0.30) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL30550979 | 0.77 | HTT (0.36) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL15335154 | 0.77 | HTT (0.36) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL20176892 | 0.77 | P2RX3 (0.36) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL22716205 | 0.73 | KDM4E (0.33) | NOS3NOS2NOS1HSP90AA1HSP90AB1 | |
| SCHEMBL18925806 | 0.73 | NOS3 (0.43) | NOS3NOS2NOS1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133225-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |