Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 5/20 | 0.34 |
| ▸ | FYN | P06241 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288597 | 0.82 | NFE2L2 (0.37) | MEN1KMT2AERN1ALDH1A1MAPT | |
| SCHEMBL5396028 | 0.81 | ALDH1A1 (0.36) | MEN1KMT2AERN1ALDH1A1MAPT | |
| SCHEMBL25847966 | 0.77 | NOS3 (0.36) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL30515887 | 0.76 | MEN1 (0.37) | MEN1KMT2AERN1ALDH1A1TDP1 | |
| SCHEMBL21579429 | 0.76 | MEN1 (0.37) | MEN1KMT2AERN1ALDH1A1TDP1 | |
| SCHEMBL28051934 | 0.74 | ALDH1A1 (0.36) | MEN1KMT2AERN1ALDH1A1MAPT | |
| SCHEMBL30550979 | 0.73 | HTT (0.36) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL31168527 | 0.73 | FYN (0.37) | P2RX3P2RX2MEN1KMT2APOLB | |
| SCHEMBL25259410 | 0.73 | MEN1 (0.30) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL15335154 | 0.73 | HTT (0.36) | MEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092047-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | JOINT STOCK COMPANY "BIOCAD" (RU) | 2018-05-24 | — | — | WO | disclosed |