Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24067302 | 0.81 | HPGD (0.41) | HSD17B10BRD4L3MBTL1HTTALDH1A1 | |
| SCHEMBL21815683 | 0.81 | HSD17B10 (0.42) | HSD17B10GSK3BOPRK1PDK1HSP90AA1 | |
| SCHEMBL31425803 | 0.78 | KRAS (0.38) | HSD17B10GSK3BTSHROPRK1ALDH1A1 | |
| SCHEMBL22450623 | 0.78 | BRD4 (0.38) | BRD4L3MBTL1ALDH1A1MTNR1AKDM4E | |
| SCHEMBL15882666 | 0.76 | ENPP3 (0.45) | HSD17B10L3MBTL1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL14884084 | 0.75 | HSD17B10 (0.43) | HSD17B10BRD4L3MBTL1GSK3BHTT | |
| SCHEMBL13745841 | 0.75 | DGAT1 (0.35) | HSD17B10BRD4GSK3BTSHROPRK1 | |
| SCHEMBL21815626 | 0.74 | LMNA (0.53) | HSD17B10TSHROPRK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30495357 | 0.74 | HSD17B10 (0.37) | HSD17B10GSK3BTSHRALDH1A1MTNR1A | |
| SCHEMBL24342347 | 0.74 | HSD17B10 (0.37) | HSD17B10GSK3BTSHRALDH1A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |