Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29273297 | 0.98 | MAPT (0.59) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL270134 | 0.81 | MAPT (0.57) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL28602564 | 0.81 | MAPT (0.57) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL4447460 | 0.81 | KMT2A (0.57) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL5331416 | 0.79 | MAPT (0.55) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL6610803 | 0.79 | MAPT (0.55) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL29679704 | 0.78 | KCNN4 (0.47) | MAPTKMT2ACYP2C19HIF1ATAAR1 | |
| SCHEMBL1195864 | 0.78 | CES1 (0.57) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL28430563 | 0.78 | MAPT (0.53) | MAPTKMT2ACYP2C19HIF1AMAPK1 | |
| SCHEMBL4441293 | 0.78 | MAPT (0.53) | MAPTKMT2ACYP2C19HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023117681-A1 | HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF CANCER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-06-29 | — | — | WO | disclosed |