SCHEMBL25848343

SCHEMBL25848343

C1=Cc2c(oc3ccc4ccc(-c5ccc(-c6nc(-c7ccc(-c8ccccc8)cc7)nc(-c7cccc8oc9ccccc9c78)n6)cc5)cc4c23)CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.35
PLA2G4A P47712 3/20 0.35
PLA2G10 O15496 1/20 0.34
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 2/20 0.30
MAPT P10636 2/20 0.30
HPGD P15428 2/20 0.30
TSHR P16473 2/20 0.30
HSD17B10 Q99714 2/20 0.30
TP53 P04637 1/20 0.30
NFKB1 P19838 1/20 0.30
MAPK1 P28482 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25848346 0.95 PLA2G2A (0.31) PLA2G2APLA2G4APLA2G10
SCHEMBL24315132 0.88 TDP1 (0.31) TDP1L3MBTL1
SCHEMBL24314490 0.88 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10PIM1CSNK2A2
SCHEMBL25846679 0.87
SCHEMBL25652508 0.87 LMNA (0.31) MAPTTSHR
SCHEMBL25652589 0.86 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10PIM1CSNK2A2
SCHEMBL24314457 0.86 KDM4E (0.31) PLA2G2APLA2G4APLA2G10KDM4EALDH1A1
SCHEMBL24971407 0.86 PLA2G2A (0.31) PLA2G2APLA2G4APLA2G10PRKDC
SCHEMBL21755976 0.86 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10
SCHEMBL24971380 0.86 BACE1 (0.31) MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132694-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-07-13 WO disclosed