Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24664428 | 0.79 | KMT2A (0.59) | KMT2AHTTCYP2C19LMNATDP1 | |
| SCHEMBL3705956 | 0.79 | KMT2A (0.59) | KMT2AHTTCYP2C19LMNATDP1 | |
| SCHEMBL1651682 | 0.77 | LMNA (0.61) | KMT2AHTTCYP2C19LMNATDP1 | |
| SCHEMBL23646273 | 0.76 | ITGB3 (0.52) | KMT2AHTTMAPK1 | |
| SCHEMBL23646232 | 0.76 | ITGB3 (0.52) | KMT2AHTTMAPK1 | |
| SCHEMBL23646203 | 0.76 | ITGB3 (0.52) | KMT2AHTTMAPK1 | |
| SCHEMBL23646283 | 0.76 | ITGB3 (0.52) | KMT2AHTTMAPK1 | |
| SCHEMBL10272740 | 0.76 | TDP1 (0.62) | KMT2AHTTCYP2C19LMNATDP1 | |
| Hydrochloric Acid SCHEMBL10806956 | 0.76 | LMNA (0.59) | KMT2AHTTCYP2C19LMNATDP1 | |
| SCHEMBL20307157 | 0.75 | KMT2A (0.57) | KMT2AHTTMEN1CYP2C9PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |