Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25853767 | 1.00 | LMNA (0.48) | LMNAKMT2AALDH1A1PDK1HTT | |
| SCHEMBL13612906 | 0.85 | KMT2A (0.55) | LMNAKMT2AALDH1A1PDK1HTT | |
| SCHEMBL25849507 | 0.81 | LMNA (0.50) | LMNAKMT2AALDH1A1HTTNPSR1 | |
| SCHEMBL25853769 | 0.79 | NAMPT (0.41) | LMNAKMT2AALDH1A1PDK1HTT | |
| SCHEMBL30622645 | 0.77 | ALDH1A1 (0.47) | LMNAKMT2AALDH1A1PDK1HTT | |
| SCHEMBL10575871 | 0.76 | KMT2A (0.45) | LMNAKMT2AALDH1A1PDK1HTT | |
| SCHEMBL10355374 | 0.76 | KMT2A (0.45) | LMNAKMT2AALDH1A1PDK1HTT | |
| SCHEMBL25853778 | 0.76 | KMT2A (0.42) | LMNAKMT2AALDH1A1PDK1HTT | |
| SCHEMBL10569417 | 0.76 | KMT2A (0.45) | LMNAKMT2AALDH1A1PDK1HTT | |
| SCHEMBL4089086 | 0.75 | LMNA (0.51) | LMNAKMT2AALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |