Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25853767 | 0.81 | LMNA (0.48) | LMNAKMT2ACYP2C19HTTMEN1 | |
| SCHEMBL25849283 | 0.81 | LMNA (0.48) | LMNAKMT2ACYP2C19HTTMEN1 | |
| SCHEMBL25851517 | 0.77 | FKBP1A (0.34) | LMNAKMT2AHTTNAMPT | |
| SCHEMBL20807970 | 0.76 | POLB (0.48) | ALDH1A1NAMPT | |
| SCHEMBL4089086 | 0.74 | LMNA (0.51) | LMNAKMT2ACYP2C19HTTMEN1 | |
| SCHEMBL1574449 | 0.72 | LMNA (0.47) | LMNAKMT2ACYP2C19HTTMEN1 | |
| SCHEMBL20034965 | 0.72 | LMNA (0.57) | LMNAKMT2ACYP2C19HTTMEN1 | |
| SCHEMBL11833951 | 0.72 | CHRNB2 (0.52) | KMT2ACYP2C19MEN1EPHX1ALDH1A1 | |
| SCHEMBL21480194 | 0.72 | CHRNB2 (0.52) | KMT2ACYP2C19MEN1EPHX1ALDH1A1 | |
| SCHEMBL1576048 | 0.71 | LMNA (0.52) | LMNAKMT2ACYP2C19HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |