Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25849457 | 0.95 | BRD4 (0.44) | BRD4CREBBPNR1H2NR1H3SLC2A1 | |
| SCHEMBL25849454 | 0.89 | SLC2A1 (0.49) | BRD4CREBBPSLC2A1BCHEACHE | |
| SCHEMBL25849408 | 0.87 | BRD4 (0.45) | BRD4CREBBPSLC2A1BCHEACHE | |
| SCHEMBL25849459 | 0.86 | BRD4 (0.41) | BRD4CREBBPNR1H2NR1H3SLC2A1 | |
| SCHEMBL29768819 | 0.85 | SLC2A1 (0.49) | BRD4CREBBPSLC2A1BCHEACHE | |
| SCHEMBL19047283 | 0.85 | SLC2A1 (0.49) | BRD4CREBBPSLC2A1BCHEACHE | |
| SCHEMBL24046937 | 0.84 | BRD4 (0.45) | BRD4CREBBPNR1H2NR1H3SLC2A1 | |
| SCHEMBL19032416 | 0.82 | SLC2A1 (0.53) | BRD4CREBBPSLC2A1KDM4EMEN1 | |
| SCHEMBL25849456 | 0.80 | NR1H2 (0.41) | BRD4CREBBPNR1H2NR1H3KDM4E | |
| SCHEMBL25849453 | 0.80 | BRD4 (0.41) | BRD4CREBBPNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181564-A1 | Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites | THE UNIVERSITY OF SHEFFIELD (GB) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181564-A1 | Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites | CYP11B2, CYP11B1, COX5B | BRD4 855/4885CREBBP 1678/4885NR1H2 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.