SCHEMBL25849461

SCHEMBL25849461

CCCCCCCCCCCCCCCC(=O)NCC(C)(C)OC

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.56
HSP90AA1 P07900 1/20 0.48
DNM1 Q05193 2/20 0.47
RECQL P46063 1/20 0.47
GAA P10253 1/20 0.46
CASP2 P42575 1/20 0.46
MEN1 O00255 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
EPHX2 P34913 1/20 0.44
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
POLB P06746 1/20 0.44
POLA1 P09884 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26046271 0.83 FAAH (0.53) FAAHHSP90AA1DNM1RECQLGAA
SCHEMBL13701833 0.82 FAAH (0.64) FAAHHSP90AA1DNM1GAACASP2
SCHEMBL12572413 0.80 FAAH (0.62) FAAHHSP90AA1DNM1CASP2MEN1
SCHEMBL31560149 0.80 FAAH (0.62) FAAHHSP90AA1DNM1CASP2MEN1
SCHEMBL13621278 0.80 FAAH (0.62) FAAHHSP90AA1DNM1CASP2MEN1
SCHEMBL25843185 0.80 FAAH (0.53) FAAHHSP90AA1DNM1RECQLGAA
SCHEMBL12285493 0.80 FAAH (0.61) FAAHHSP90AA1DNM1RECQLCASP2
SCHEMBL11222029 0.79 FAAH (0.60) FAAHHSP90AA1DNM1CASP2MEN1
SCHEMBL11242257 0.77 FAAH (0.58) FAAHHSP90AA1DNM1CASP2MEN1
SCHEMBL3391250 0.77 RECQL (0.81) FAAHHSP90AA1DNM1RECQLGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 FAAH 2901/4885HSP90AA1 1924/4885DNM1 376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.