SCHEMBL26046271

SCHEMBL26046271

CCCCCCCCCCCCCCCC(=O)NCC(C)(S)OC

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.53
HSP90AA1 P07900 1/20 0.46
DNM1 Q05193 2/20 0.45
RECQL P46063 1/20 0.44
GAA P10253 1/20 0.44
CASP2 P42575 1/20 0.43
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42
TRPV1 Q8NER1 1/20 0.42
EPHX2 P34913 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849461 0.83 FAAH (0.56) FAAHHSP90AA1DNM1RECQLGAA
SCHEMBL13701833 0.79 FAAH (0.64) FAAHHSP90AA1DNM1GAACASP2
SCHEMBL13621278 0.78 FAAH (0.62) FAAHHSP90AA1DNM1CASP2CNR1
SCHEMBL12572413 0.78 FAAH (0.62) FAAHHSP90AA1DNM1CASP2CNR1
SCHEMBL31560149 0.78 FAAH (0.62) FAAHHSP90AA1DNM1CASP2CNR1
SCHEMBL25843185 0.77 FAAH (0.53) FAAHHSP90AA1DNM1RECQLGAA
SCHEMBL12285493 0.77 FAAH (0.61) FAAHHSP90AA1DNM1RECQLCASP2
SCHEMBL11222029 0.76 FAAH (0.60) FAAHHSP90AA1DNM1CASP2MEN1
SCHEMBL8435172 0.75 FAAH (0.46) FAAHGAACNR1CNR2EPHX2
SCHEMBL11242257 0.75 FAAH (0.58) FAAHHSP90AA1DNM1CASP2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 FAAH 4742/4885HSP90AA1 919/4885DNM1 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.