SCHEMBL25849578

SCHEMBL25849578

CCN1C(=O)C(=C/C=C2\N(C)c3nc4ccccc4nc3N2c2c(C(C)C)cccc2C(C)C)C(=O)N(CC)C1=S

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MDM2 Q00987 3/20 0.38
POLB P06746 2/20 0.38
HPGD P15428 2/20 0.38
KDM4E B2RXH2 2/20 0.38
THRB P10828 1/20 0.38
HTT P42858 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
DPP4 P27487 4/20 0.38
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
TNFRSF1A P19438 5/20 0.36
ANPEP P15144 4/20 0.34
ENPP3 O14638 1/20 0.33
MAPK1 P28482 3/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849572 0.83 MAPK1 (0.31) DPP4NR1H2NR1H3MAPK1
SCHEMBL25849586 0.83 DPP4 (0.41) MAPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL25849580 0.82 DPP4 (0.36) DPP4NR1H2NR1H3ANPEP
SCHEMBL26300124 0.81 DPP4 (0.39) MAPTALDH1A1KDM4EL3MBTL1DPP4
SCHEMBL25849554 0.79 DPP4 (0.36) MAPTKMT2AMEN1DPP4NR1H2
SCHEMBL23338685 0.77 MAPK1 (0.33) DPP4NR1H2NR1H3MAPK1
SCHEMBL25849569 0.77 DPP4 (0.36) KDM4EHTTDPP4NR1H2NR1H3
SCHEMBL23338686 0.76 DPP4 (0.38) MAPTALDH1A1KDM4EHTTL3MBTL1
SCHEMBL23337880 0.74 DPP4 (0.36) ALDH1A1DPP4NR1H2NR1H3ANPEP
SCHEMBL25849583 0.73 DPP4 (0.34) KMT2ADPP4NR1H2NR1H3ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed