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SCHEMBL25849760

SCHEMBL25849760

CC(C)c1cccc(C(C)C)c1-c1ccc2c(c1)C(C)(C)c1cc(C=C3C(=O)c4cc5ccccc5cc4C3=O)sc1N2C

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ THRB P10828 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ RECQL P46063 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25850783 0.90 ALDH1A1 (0.30) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL25850788 0.90 ALDH1A1 (0.30) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL25849755 0.88 POLB (0.33) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL25849765 0.88 CREBBP (0.32) —
SCHEMBL25849750 0.86 ALDH1A1 (0.32) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL25849745 0.86 MAPT (0.32) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL25849759 0.85 LCK (0.33) ALDH1A1MAPTHPGDKMT2A
SCHEMBL25849768 0.85 NR1H3 (0.34) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL23331571 0.85 DPP4 (0.35) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL25849711 0.82 MAPT (0.41) ALDH1A1MAPTTHRBHPGDRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 — — US disclosed