SCHEMBL25849755

SCHEMBL25849755

Cc1cccc(C)c1-c1ccc2c(c1)C(C)(C)c1cc(C=C3C(=O)c4cc5ccccc5cc4C3=O)sc1N2C

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
HPGD P15428 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 1/20 0.31
CREBBP Q92793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849750 0.94 ALDH1A1 (0.32) POLBALDH1A1MAPTTHRBHPGD
SCHEMBL25849765 0.90 CREBBP (0.32) CREBBP
SCHEMBL25849745 0.89 MAPT (0.32) POLBALDH1A1MAPTTHRBHPGD
SCHEMBL25849760 0.88 ALDH1A1 (0.31) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL25850805 0.86 ALDH1A1 (0.30) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL25849753 0.85 RET (0.36) POLBL3MBTL1ALDH1A1MAPTKMT2A
SCHEMBL25849711 0.84 MAPT (0.41) POLBL3MBTL1ALDH1A1MAPTTHRB
SCHEMBL25849768 0.82 NR1H3 (0.34) POLBALDH1A1MAPTTHRBHPGD
SCHEMBL25850749 0.80 GRIA1 (0.35) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL25850660 0.80 ALDH1A1 (0.32) ALDH1A1MAPTTHRBHPGDRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed