Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320870 | 0.89 | MEN1 (0.50) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL4526992 | 0.88 | L3MBTL1 (0.50) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL31667777 | 0.88 | L3MBTL1 (0.50) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL3117862 | 0.87 | MEN1 (0.44) | KMT2AMEN1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL25934543 | 0.87 | L3MBTL1 (0.49) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL13825505 | 0.86 | MEN1 (0.43) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL13215086 | 0.86 | AKT1 (0.48) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL23746079 | 0.85 | MEP1B (0.46) | KMT2AMEN1 | |
| SCHEMBL2578593 | 0.85 | MEN1 (0.42) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL3143341 | 0.85 | MEN1 (0.42) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239830-A1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2024-07-18 | — | — | US | disclosed |
| US-20240239830-A1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2024-07-18 | — | — | US | disclosed |
| US-11697666-B2 | Methods of preparing carbanucleosides using amides | GILEAD SCIENCES, INC. (US) | 2023-07-11 | — | — | US | disclosed |
| US-11697666-B2 | Methods of preparing carbanucleosides using amides | GILEAD SCIENCES, INC. (US) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697666-B2 | Methods of preparing carbanucleosides using amides | NCL, DUT, POLN | KMT2A 1870/4885MEN1 1682/4885LMNA 154/4885 |
| US-20240239830-A1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | NCL, DUT, POLN | KMT2A 1870/4885MEN1 1682/4885LMNA 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.