SCHEMBL25853283

SCHEMBL25853283

Cc1cccc(Nc2cccc(Nc3ccccc3)c2)c1

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.95
MAPT P10636 6/20 0.73
MEN1 O00255 2/20 0.73
KMT2A Q03164 2/20 0.73
ALDH1A1 P00352 2/20 0.73
AR P10275 1/20 0.73
HPGD P15428 1/20 0.60
KCNH3 Q9ULD8 1/20 0.56
HSD17B10 Q99714 3/20 0.55
CYP3A4 P08684 2/20 0.54
TSHR P16473 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
LMNA P02545 2/20 0.54
KDM4E B2RXH2 1/20 0.54
GAA P10253 1/20 0.54
GFER P55789 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234363 0.98 NPSR1 (1.00) NPSR1MAPTMEN1KMT2AALDH1A1
SCHEMBL30416120 0.98 NPSR1 (1.00) NPSR1MAPTMEN1KMT2AALDH1A1
SCHEMBL27928604 0.95 NPSR1 (0.95) NPSR1MAPTMEN1KMT2AALDH1A1
SCHEMBL19866508 0.95 NPSR1 (0.95) NPSR1MAPTMEN1KMT2AALDH1A1
SCHEMBL9158496 0.93 NPSR1 (0.82) NPSR1MAPTMEN1KMT2AALDH1A1
Biphenyl SCHEMBL9701776 0.91 NPSR1 (0.88) NPSR1MAPTMEN1KMT2AALDH1A1
Trimethylammonium SCHEMBL28373266 0.91 NPSR1 (0.88) NPSR1MAPTMEN1KMT2AALDH1A1
SCHEMBL1922070 0.91 NPSR1 (0.86) NPSR1MAPTMEN1KMT2AALDH1A1
SCHEMBL1690867 0.91 NPSR1 (0.78) NPSR1MAPTMEN1KMT2AALDH1A1
SCHEMBL30145137 0.91 NPSR1 (0.86) NPSR1MAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225208-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225208-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR LIGHT EMITTING ELEMENT CRY1, PER2, CRY2 NPSR1 3882/4885MAPT 2324/4885MEN1 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.