Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.45 |
| ▸ | PGR | P06401 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21340498 | 0.93 | HIF1A (0.43) | HIF1ANR3C1PGRLMNAAR | |
| Formocortal SCHEMBL4354 | 0.92 | HIF1A (0.52) | HIF1ANR3C1PGRLMNAAR | |
| Formocortal SCHEMBL21234455 | 0.92 | HIF1A (0.52) | HIF1ANR3C1PGRLMNAAR | |
| Formocortal SCHEMBL5484249 | 0.92 | HIF1A (0.52) | HIF1ANR3C1PGRLMNAAR | |
| Formocortal SCHEMBL4353 | 0.92 | HIF1A (0.52) | HIF1ANR3C1PGRLMNAAR | |
| SCHEMBL21340510 | 0.86 | HIF1A (0.46) | HIF1ANR3C1PGRLMNAAR | |
| SCHEMBL6832364 | 0.83 | CYP3A4 (0.54) | HIF1ANR3C1PGRLMNAAR | |
| SCHEMBL5034365 | 0.83 | CYP3A4 (0.54) | HIF1ANR3C1PGRLMNAAR | |
| SCHEMBL21234457 | 0.83 | CYP3A4 (0.50) | HIF1ANR3C1PGRLMNAAR | |
| Formocortal SCHEMBL6915676 | 0.82 | HIF1A (0.43) | HIF1ANR3C1PGRLMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230225975-A1 | DEXAMETHASONE PRODRUG COMPOSITIONS AND USES THEREOF | RIPPLE THERAPEUTICS CORPORATION (CA) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230225975-A1 | DEXAMETHASONE PRODRUG COMPOSITIONS AND USES THEREOF | NR3C1, NR3C2, CYP21A2 | HIF1A 1543/4885NR3C1 1/4885PGR 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.