Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.52 |
| ▸ | PGR | P06401 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | AR | P10275 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formocortal SCHEMBL5484249 | 1.00 | HIF1A (0.52) | HIF1ANR3C1PGRLMNAAR | |
| Formocortal SCHEMBL4353 | 1.00 | HIF1A (0.52) | HIF1ANR3C1PGRLMNAAR | |
| Formocortal SCHEMBL4354 | 1.00 | HIF1A (0.52) | HIF1ANR3C1PGRLMNAAR | |
| SCHEMBL25854502 | 0.92 | HIF1A (0.45) | HIF1ANR3C1PGRLMNAAR | |
| SCHEMBL6832364 | 0.92 | CYP3A4 (0.54) | HIF1ANR3C1PGRLMNAAR | |
| SCHEMBL5034365 | 0.92 | CYP3A4 (0.54) | HIF1ANR3C1PGRLMNAAR | |
| SCHEMBL21234457 | 0.91 | CYP3A4 (0.50) | HIF1ANR3C1PGRLMNAAR | |
| SCHEMBL21340498 | 0.90 | HIF1A (0.43) | HIF1ANR3C1PGRLMNAAR | |
| Formocortal SCHEMBL6915676 | 0.90 | HIF1A (0.43) | HIF1ANR3C1PGRLMNAAR | |
| Cicortonide SCHEMBL2110020 | 0.89 | NR3C1 (0.51) | HIF1ANR3C1PGRLMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210113457-A1 | GLASS FORMULATIONS AND USES THEREOF | RIPPLE THERAPEUTICS CORPORATION (CA) | 2021-04-22 | — | — | US | disclosed |
| US-20210030667-A1 | OCULAR INSERTS COMPRISING A COVALENTLY LINKED STEROID DIMER | RIPPLE THERAPEUTICS CORPORATION (CA) | 2021-02-04 | — | — | US | disclosed |
| US-10632075-B2 | Glass formulations and uses thereof | RIPPLE THERAPEUTICS CORPORATION (CA) | 2020-04-28 | — | — | US | disclosed |
| US-20190275167-A1 | GLASS FORMULATIONS AND USES THEREOF | RIPPLE THERAPEUTICS CORPORATION (CA) | 2019-09-12 | — | — | US | disclosed |
| WO-2019148291-A1 | OCULAR INSERTS COMPRISING A COVALENTLY LINKED STEROID DIMER | INTERFACE BIOLOGICS, INC. (CA) | 2019-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190275167-A1 | GLASS FORMULATIONS AND USES THEREOF | GBA2, AGER, GBA1 | HIF1A 2789/4885NR3C1 1714/4885PGR 84/4885 |
| US-20210030667-A1 | OCULAR INSERTS COMPRISING A COVALENTLY LINKED STEROID DIMER | SHBG, SERPINA6, UACA | HIF1A 4664/4885NR3C1 12/4885PGR 15/4885 |
| US-20210113457-A1 | GLASS FORMULATIONS AND USES THEREOF | GBA2, AGER, GBA1 | HIF1A 2789/4885NR3C1 1714/4885PGR 84/4885 |
| US-10632075-B2 | Glass formulations and uses thereof | GBA2, AGER, GBA1 | HIF1A 2789/4885NR3C1 1714/4885PGR 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.