Formocortal

Formocortal

SCHEMBL5484249

CC(=O)OCC(=O)[C@@]12OC(C)(C)O[C@H]1C[C@H]1[C@@H]3CC(C=O)=C4C=C(OCCCl)CC[C@]4(C)C3(F)[C@@H](O)C[C@@]12C

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 7/20 0.52
▸ NR3C1 P04150 6/20 0.52
▸ PGR P06401 6/20 0.52
▸ LMNA P02545 6/20 0.52
▸ AR P10275 3/20 0.52
▸ ALDH1A1 P00352 1/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ KMT2A Q03164 1/20 0.52
▸ CYP3A4 P08684 7/20 0.51
▸ USP2 O75604 2/20 0.51
▸ MAPT P10636 2/20 0.49
▸ NPSR1 Q6W5P4 2/20 0.49
▸ CNR1 P21554 1/20 0.49
▸ KCNH2 Q12809 1/20 0.49
▸ HSD17B10 Q99714 2/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ NR1I2 O75469 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formocortal SCHEMBL21234455 1.00 HIF1A (0.52) HIF1ANR3C1PGRLMNAAR
Formocortal SCHEMBL4353 1.00 HIF1A (0.52) HIF1ANR3C1PGRLMNAAR
Formocortal SCHEMBL4354 1.00 HIF1A (0.52) HIF1ANR3C1PGRLMNAAR
SCHEMBL25854502 0.92 HIF1A (0.45) HIF1ANR3C1PGRLMNAAR
SCHEMBL6832364 0.92 CYP3A4 (0.54) HIF1ANR3C1PGRLMNAAR
SCHEMBL5034365 0.92 CYP3A4 (0.54) HIF1ANR3C1PGRLMNAAR
SCHEMBL21234457 0.91 CYP3A4 (0.50) HIF1ANR3C1PGRLMNAAR
SCHEMBL21340498 0.90 HIF1A (0.43) HIF1ANR3C1PGRLMNAAR
Formocortal SCHEMBL6915676 0.90 HIF1A (0.43) HIF1ANR3C1PGRLMNAAR
Cicortonide SCHEMBL2110020 0.89 NR3C1 (0.51) HIF1ANR3C1PGRLMNAAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070021360-A1 Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase EPIGENESIS PHARMACEUTICALS, LLC 2007-01-25 — — US claimed
US-20070021360-A1 Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase EPIGENESIS PHARMACEUTICALS, LLC 2007-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021360-A1 Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase RECQL, GSS, DDX17 HIF1A 1076/4885NR3C1 104/4885PGR 965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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