SCHEMBL25855320

SCHEMBL25855320

C=CC(=O)Oc1ccc(-c2ccc3c(sc4c(C)c(OC(=O)C=C)ccc43)c2OC(F)(F)F)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.32
FFAR4 Q5NUL3 3/20 0.31
FFAR1 O14842 2/20 0.31
CTSA P10619 3/20 0.31
ESR1 P03372 1/20 0.31
ABL1 P00519 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
CSF1R P07333 1/20 0.31
LYN P07948 1/20 0.31
KIT P10721 1/20 0.31
SRC P12931 1/20 0.31
FLT1 P17948 1/20 0.31
FLT4 P35916 1/20 0.31
KDR P35968 1/20 0.31
FLT3 P36888 1/20 0.31
BLK P51451 1/20 0.31
SCN5A Q14524 1/20 0.31
SCN9A Q15858 1/20 0.31
POLQ O75417 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25856225 0.92 THRB (0.32) THRBFFAR4FFAR1CTSAESR1
SCHEMBL25856373 0.92 FFAR4 (0.33) THRBFFAR4FFAR1ESR1ABL1
SCHEMBL25854949 0.89 FFAR4 (0.31) THRBFFAR4FFAR1ESR1
SCHEMBL25856230 0.88 ABL1 (0.34) THRBFFAR4CTSAESR1ABL1
SCHEMBL25856104 0.88 FFAR4 (0.31) THRBFFAR4ESR1
SCHEMBL25855189 0.88 KMT2A (0.35) THRB
SCHEMBL25853708 0.87 TYMS (0.32) THRB
SCHEMBL25855184 0.86 THRB (0.38) THRB
SCHEMBL25855322 0.86 ELANE (0.34) FFAR4FFAR1ABL1LCKFYN
SCHEMBL25855044 0.85 THRB (0.36) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed