SCHEMBL25856230

SCHEMBL25856230

C=CC(=O)Oc1ccc(-c2ccc3c(sc4c(OC(F)(F)F)c(OC(=O)C=C)ccc43)c2OC)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 3/20 0.34
LCK P06239 1/20 0.34
FYN P06241 1/20 0.34
CSF1R P07333 1/20 0.34
LYN P07948 1/20 0.34
KIT P10721 1/20 0.34
SRC P12931 1/20 0.34
FLT1 P17948 1/20 0.34
FLT4 P35916 1/20 0.34
KDR P35968 1/20 0.34
FLT3 P36888 1/20 0.34
BLK P51451 1/20 0.34
THRB P10828 2/20 0.32
CTSA P10619 3/20 0.32
POLQ O75417 1/20 0.32
FFAR4 Q5NUL3 2/20 0.32
ESR1 P03372 1/20 0.31
PTPN1 P18031 1/20 0.31
ADORA3 P0DMS8 1/20 0.30
PTGDR2 Q9Y5Y4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25856373 0.94 FFAR4 (0.33) ABL1LCKFYNCSF1RLYN
SCHEMBL25855617 0.91 THRB (0.36) THRBADORA3
SCHEMBL25856225 0.90 THRB (0.32) ABL1LCKFYNCSF1RLYN
SCHEMBL25856165 0.90 FFAR4 (0.32) THRBFFAR4ESR1
SCHEMBL25853852 0.88 TYMS (0.32) THRB
SCHEMBL25856008 0.88 PTGDR2 (0.32) THRBPTGDR2
SCHEMBL25855320 0.88 THRB (0.32) ABL1LCKFYNCSF1RLYN
SCHEMBL25856321 0.88 FFAR4 (0.31) THRBFFAR4ESR1
SCHEMBL25854949 0.87 FFAR4 (0.31) THRBFFAR4ESR1
SCHEMBL25854859 0.87 THRB (0.34) THRBESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed