SCHEMBL25856373

SCHEMBL25856373

C=CC(=O)Oc1ccc(-c2ccc3c(sc4c(OC(F)(F)F)c(OC(=O)C=C)ccc43)c2OC(F)(F)F)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.33
ESR1 P03372 2/20 0.32
THRB P10828 2/20 0.32
TYMS P04818 1/20 0.32
ERCC5 P28715 1/20 0.31
FEN1 P39748 1/20 0.31
ABL1 P00519 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
CSF1R P07333 1/20 0.31
LYN P07948 1/20 0.31
KIT P10721 1/20 0.31
SRC P12931 1/20 0.31
FLT1 P17948 1/20 0.31
FLT4 P35916 1/20 0.31
KDR P35968 1/20 0.31
FLT3 P36888 1/20 0.31
BLK P51451 1/20 0.31
SCN5A Q14524 1/20 0.31
SCN9A Q15858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25856230 0.94 ABL1 (0.34) FFAR4ESR1THRBABL1LCK
SCHEMBL25856165 0.94 FFAR4 (0.32) FFAR4ESR1THRBTYMSFFAR1
SCHEMBL25854949 0.93 FFAR4 (0.31) FFAR4ESR1THRBTYMSFFAR1
SCHEMBL25856225 0.92 THRB (0.32) FFAR4ESR1THRBABL1LCK
SCHEMBL25856321 0.92 FFAR4 (0.31) FFAR4ESR1THRB
SCHEMBL25855320 0.92 THRB (0.32) FFAR4ESR1THRBABL1LCK
SCHEMBL25856104 0.92 FFAR4 (0.31) FFAR4ESR1THRB
SCHEMBL25854311 0.89 TYMS (0.35) THRBTYMS
SCHEMBL25854666 0.86 ESR1 (0.38) FFAR4ESR1THRBSCN5ASCN9A
SCHEMBL25856161 0.85 ESR1 (0.39) ESR1THRBTEK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed