Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14349999 | 0.88 | TUBB4A (0.49) | RAB9ASMN1; SMN2NPC1MAPTPOLB | |
| SCHEMBL2464156 | 0.86 | MEN1 (0.49) | RAB9ASMN1; SMN2NPC1MAPTPOLB | |
| SCHEMBL19614838 | 0.84 | MEN1 (0.48) | RAB9ASMN1; SMN2NPC1MAPTPOLB | |
| SCHEMBL2465134 | 0.84 | MEN1 (0.51) | RAB9ASMN1; SMN2NPC1MAPTPOLB | |
| SCHEMBL7116824 | 0.84 | TGM2 (0.54) | RAB9ASMN1; SMN2NPC1MAPTPOLB | |
| SCHEMBL24341135 | 0.84 | SMN1; SMN2 (0.52) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL9435780 | 0.84 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1MAPTPOLB | |
| SCHEMBL8867866 | 0.83 | MEN1 (0.47) | RAB9ASMN1; SMN2NPC1MAPTPOLB | |
| SCHEMBL8589506 | 0.83 | MEN1 (0.47) | RAB9ASMN1; SMN2NPC1MAPTPOLB | |
| SCHEMBL8867871 | 0.83 | MEN1 (0.47) | RAB9ASMN1; SMN2NPC1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458069-B1 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF | MERSANA THERAPEUTICS INC (US) | 2023-07-05 | — | — | EP | disclosed |