Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.63 |
| ▸ | PPARG | P37231 | 7/20 | 0.63 |
| ▸ | PPARD | Q03181 | 7/20 | 0.63 |
| ▸ | PPARA | Q07869 | 7/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TLR2 | O60603 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | FABP4 | P15090 | 2/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.63 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Ethylhexanoic Acid SCHEMBL3127804 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| 2-Ethylhexanoic Acid SCHEMBL28500508 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| 2-Ethylhexanoic Acid SCHEMBL18009668 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Palmitic Acid SCHEMBL633826 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Myristic Acid SCHEMBL28575932 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Stearic Acid SCHEMBL7028397 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Stearic Acid SCHEMBL3442014 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Behenic Acid SCHEMBL6871644 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| 2-Ethylhexanoic Acid SCHEMBL320959 | 0.98 | CA2 (0.71) | CA2MAPK1GPR84PPARGPPARD | |
| 2-Ethylhexanoic Acid SCHEMBL2429690 | 0.98 | CA2 (0.77) | CA2MAPK1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5831133-A | REDUCTION OF ALDEHYDES, KETONES, ESTERS AND LACTONES | FIRMENICH SA (CH) | 1998-11-03 | — | — | US | claimed |
| US-4064303-A | OXIDATION CATALYST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-12-20 | — | — | US | claimed |
| CN-115137664-A | Cosmetic composition containing radix astragali peptide ripened product for improving skin activity | 株式会社现代百朗德 | 2022-10-04 | — | — | CN | disclosed |
| EP-2550954-B1 | VASELINE-LIKE COMPOSITION, AND COSMETIC PREPARATION | NISSHIN OILLIO GROUP LTD (JP) | 2020-03-04 | — | — | EP | disclosed |
| CN-107108837-A | For delivering activating agent to the thermoplastic polyurethane film of skin surface | 路博润先进材料公司 | 2017-08-29 | — | — | CN | disclosed |
| EP-3197905-A1 | METHOD FOR PRODUCING ETHYLENEDIALKYLPHOSPHINIC ACIDS, ESTERS AND SALTS, AND THE USE THEREOF AS FLAME RETARDANTS | Clariant Plastics & Coatings Ltd (CH) | 2017-08-02 | — | — | EP | disclosed |
| CN-106309421-A | Medical compound and cosmetic compound | 沃凯索法株式会社 | 2017-01-11 | — | — | CN | disclosed |
| CN-103800313-B | pharmaceutical composition and cosmetic composition | 沃凯索法株式会社 | 2016-09-14 | — | — | CN | disclosed |
| WO-2016045976-A1 | METHOD FOR PRODUCING ETHYLENEDIALKYLPHOSPHINIC ACIDS, ESTERS AND SALTS, AND THE USE THEREOF AS FLAME RETARDANTS | CLARIANT INTERNATIONAL LTD (CH) | 2016-03-31 | — | — | WO | disclosed |
| CN-102883733-B | AGE production inhibitor | ORYZA OIL & FAT CHEM | 2014-08-13 | — | — | CN | disclosed |
| CN-103800313-A | Novel derivatives of cyclic compound and the use thereof | WONKISOPHARM CO LTD | 2014-05-21 | — | — | CN | disclosed |
| CN-101547886-A | Novel derivative of cyclic compound and use thereof | WONKISOPHARM CO LTD (KR) | 2009-09-30 | — | — | CN | disclosed |
| CN-100486683-C | Fine particle disperant and cosmetic, paint, ink, memorizing material and lubricant containing the dispersant | NISSHIN OILLIO GROUP LTD (JP) | 2009-05-13 | — | — | CN | disclosed |
| CN-100467108-C | Fine particle dispersant and cosmetics, paints, inks, memory materials and lubricants containing the same | NISSHIN OILLIO GROUP LTD (JP) | 2009-03-11 | — | — | CN | disclosed |
| CN-1933801-A | Use of (2-hydroxyphenyl) alcohols and cosmetic or therapeutic preparations containing said compounds | SYMRISE GMBH & CO KG (DE) | 2007-03-21 | — | — | CN | disclosed |
| CN-1863543-A | Dietetic composition | ORYZA OIL & FAT CHEM (JP) | 2006-11-15 | — | — | CN | disclosed |
| CN-1649664-A | Fine particle dispersant and cosmetics, paints, inks, memory materials and lubricants containing the same | NISSHIN OILLIO GROUP LTD (JP) | 2005-08-03 | — | — | CN | disclosed |
| CN-1642629-A | Fine particle disperant and cosmetic, paint, ink, memorizing material and lubricant containing the dispersant | NISSHIN OILLIO GROUP LTD (JP) | 2005-07-20 | — | — | CN | disclosed |
| EP-0019584-B1 | OLIGOMERS WITH PERFLUOR ALKYL END GROUPS THAT CONTAIN MERCAPTO GROUPS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS SUFACE-ACTIVE SUBSTANCES AND AS ADDITIVES IN FIRE-EXTINGUISHING COMPOSITIONS | CIBA-GEIGY AG (CH) | 1984-11-14 | — | — | EP | disclosed |
| EP-0019584-A2 | Oligomers with perfluor alkyl end groups that contain mercapto groups, process for their preparation and their use as suface-active substances and as additives in fire-extinguishing compositions | CIBA-GEIGY AG (CH) | 1980-11-26 | — | — | EP | disclosed |