Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.63 |
| ▸ | PPARG | P37231 | 7/20 | 0.63 |
| ▸ | PPARD | Q03181 | 7/20 | 0.63 |
| ▸ | PPARA | Q07869 | 7/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TLR2 | O60603 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | FABP4 | P15090 | 2/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.63 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Ethylhexanoic Acid SCHEMBL3127804 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| 2-Ethylhexanoic Acid SCHEMBL28500508 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| 2-Ethylhexanoic Acid SCHEMBL18009668 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Stearic Acid SCHEMBL2585578 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Palmitic Acid SCHEMBL633826 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Myristic Acid SCHEMBL28575932 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Stearic Acid SCHEMBL3442014 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Behenic Acid SCHEMBL6871644 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| 2-Ethylhexanoic Acid SCHEMBL320959 | 0.98 | CA2 (0.71) | CA2MAPK1GPR84PPARGPPARD | |
| 2-Ethylhexanoic Acid SCHEMBL2429690 | 0.98 | CA2 (0.77) | CA2MAPK1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736545-B1 | Dextrin ester of fatty acids and use thereof | CHIBA FLOUR MILLING (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-5840883-A | COSMETICS, DRUGS, COATING OR INK BASE | CHIBA FLOUR MILLING CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0736545-A2 | Dextrin ester of fatty acids and use thereof | Chiba Flour Milling Co., Ltd. (JP) | 1996-10-09 | — | — | EP | disclosed |