Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.63 |
| ▸ | PPARG | P37231 | 7/20 | 0.63 |
| ▸ | PPARD | Q03181 | 7/20 | 0.63 |
| ▸ | PPARA | Q07869 | 7/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TLR2 | O60603 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | FABP4 | P15090 | 2/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.63 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Ethylhexanoic Acid SCHEMBL3127804 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| 2-Ethylhexanoic Acid SCHEMBL28500508 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| 2-Ethylhexanoic Acid SCHEMBL18009668 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Stearic Acid SCHEMBL2585578 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Palmitic Acid SCHEMBL633826 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Myristic Acid SCHEMBL28575932 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Stearic Acid SCHEMBL7028397 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| Behenic Acid SCHEMBL6871644 | 1.00 | CA2 (0.74) | CA2MAPK1GPR84PPARGPPARD | |
| 2-Ethylhexanoic Acid SCHEMBL320959 | 0.98 | CA2 (0.71) | CA2MAPK1GPR84PPARGPPARD | |
| 2-Ethylhexanoic Acid SCHEMBL2429690 | 0.98 | CA2 (0.77) | CA2MAPK1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109498478-B | Oil-soluble fullerene external composition | 北京福纳康生物技术有限公司 | 2021-01-29 | — | — | CN | disclosed |
| EP-1488850-B1 | FINE PARTICLE DISPERSANT, AND COSMETICS, COATING MATERIALS, INKS, STORAGE MATERIALS AND LUBRICANTS, CONTAINING THE SAME | NISSHIN OILLIO GROUP LTD (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-1491250-B1 | Use of a dispersant for fine particles in cosmetics | NISSHIN OILLIO GROUP LTD (JP) | 2013-05-22 | — | — | EP | disclosed |
| EP-2550954-A1 | VASELINE-LIKE COMPOSITION, AND COSMETIC PREPARATION | The Nisshin Oillio Group, Ltd. (JP) | 2013-01-30 | — | — | EP | disclosed |
| US-20130005808-A1 | VASELINE-LIKE COMPOSITION AND COSMETIC | The Nisshin OilliO Group ,Ltd. (JP) | 2013-01-03 | — | — | US | disclosed |
| US-8309109-B2 | Cosmetic and method for production thereof | HAKUTO CO., LTD. (JP) | 2012-11-13 | — | — | US | disclosed |
| US-7812056-B2 | Fine particle disperant and cosmetic, paint, ink, memorizing material and lubricant containing the dispersant | The Nisshi OilliO Group, Ltd. (JP) | 2010-10-12 | — | — | US | disclosed |
| US-20090280149-A1 | Cosmetic and Method for Production Thereof | TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) (SE) | 2009-11-12 | — | — | US | disclosed |
| EP-2044927-A1 | COSMETIC AND METHOD FOR PRODUCTION THEREOF | Hakuto Co., Ltd (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-20050106198-A1 | Fine particle disperant and cosmetic, paint, ink, memorizing material and lubricant containing the dispersant | THE NISSHIN OILLIO GROUP, LTD. (JP) | 2005-05-19 | — | — | US | disclosed |
| US-20050042181-A1 | Fine particle disperant and cosmetic, paint, ink, memorizing material and lubricant containing the dispersant | THE NISSHIN OILLIO GROUP, LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| EP-1488850-A1 | FINE PARTICLE DISPERSANT, AND COSMETICS, COATING MATERIALS, INKS, STORAGE MATERIALS AND LUBRICANTS, CONTAINING THE SAME | The Nisshin OilliO Group, Ltd. (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050042181-A1 | Fine particle disperant and cosmetic, paint, ink, memorizing material and lubricant containing the dispersant | DERL1, DRD1, FDFT1 | CA2 2601/4885MAPK1 2682/4885GPR84 516/4885 |
| US-20090280149-A1 | Cosmetic and Method for Production Thereof | CD44, UGCG, FUCA1 | CA2 2155/4885MAPK1 2008/4885GPR84 1087/4885 |
| US-20050106198-A1 | Fine particle disperant and cosmetic, paint, ink, memorizing material and lubricant containing the dispersant | DERL1, ELOVL1, RPL39 | CA2 2028/4885MAPK1 3923/4885GPR84 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.