Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25301909 | 1.00 | ALDH1A1 (0.43) | ALDH1A1NLRP3GAAMAPTKDM4E | |
| SCHEMBL25862285 | 1.00 | ALDH1A1 (0.43) | ALDH1A1NLRP3GAAMAPTKDM4E | |
| SCHEMBL25864503 | 0.87 | ALDH1A1 (0.39) | ALDH1A1GAAMAPTKDM4EHSD17B10 | |
| SCHEMBL30488479 | 0.85 | NLRP3 (0.56) | ALDH1A1NLRP3GAAMAPTKDM4E | |
| SCHEMBL25300762 | 0.85 | NLRP3 (0.56) | ALDH1A1NLRP3GAAMAPTKDM4E | |
| SCHEMBL26516981 | 0.85 | KMT2A (0.49) | ALDH1A1NLRP3GAAMAPTKDM4E | |
| SCHEMBL26117756 | 0.85 | KMT2A (0.49) | ALDH1A1NLRP3GAAMAPTKDM4E | |
| SCHEMBL25855650 | 0.84 | NLRP3 (0.40) | ALDH1A1NLRP3GAAMAPTKDM4E | |
| SCHEMBL25856084 | 0.84 | NLRP3 (0.48) | ALDH1A1NLRP3GAAMAPTKDM4E | |
| SCHEMBL29030531 | 0.83 | NLRP3 (0.46) | ALDH1A1NLRP3GAAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |